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Research Statement My clinical background and strong interest in basic immunobiology have led me to integrate basic research into more pathogenesis and treatment of diseases. The basic research in my laboratory is focused on understanding the biological consequences arising from the interaction between core molecules...

Autoimmune-mediated destruction of beta cells is the predominant cause of Type I diabetes (TIDM). Beta cell replacement through pancreatic islet cell transplantation is a theoretically attractive treatment for type 1 diabetes. Indeed recent clinical successes support this notion, but also reveal significant limitations of this...

Associate Professor, University of Chicago Dr. Alegre is a basic immunology researcher who focuses on the mechanisms that induce or maintain tolerance in T cells, as well as on the environmental signals that can prevent or break this tolerance. She completed her clinical training in...

Rebecca Lipton, Ph.D., M.P.H., B.S.N., is an Associate Professor at the University of Chicago in the Section of Pediatric Endocrinology. The overall goal of her research is to understand the risk factors and social implications of diabetes, with particular reference to minorities and children. Her...

Genetics and Biology of Diabetes Mellitus and its Complications Your genes play an important role in determining if you will develop diabetes during your lifetime. The research in the Bell and Cox laboratories is focused on identifying the genes and pathways that determine susceptibility to...

Professor of Medicine Dr. Conzen is an expert in the diagnosis and treatment of breast cancer. She has a special clinical interest in the multidisciplinary care of locally advanced breast cancers, which may require chemotherapy and radiation therapy prior to surgical resection. Dr. Conzen’s research...

Martin Boyer Professor of Medicine Associate Section Chief for Research Dr. Chang is the director of the University of Chicago’s Digestive Diseases Research Core Center. He is researching host-microbial interactions of the intestine, particularly in defining communication signals/pathways that are involved in maintaining intestinal homeostasis....