Monogenic diabetes is a rare form of diabetes caused by genetic mutation. Between 1 and 3 percent of people with diabetes have monogenic diabetes. More than 20 genes have been linked to monogenic diabetes, and a mutation in any single one of these identified genes can cause a child or adult to develop the condition.
Forms of monogenic diabetes include neonatal diabetes, which can be permanent or transient, and MODY (Maturity Onset Diabetes of the Young), typically diagnosed in late childhood, adolescence or early adulthood.
Monogenic diabetes is often misdiagnosed as one of the more common forms — type 1 or type 2 diabetes. Because an accurate diagnosis is critical to finding the best possible treatment plan, genetic testing is often recommended for diabetes patients who meet certain criteria.
The Kovler Diabetes Center, recognized as one of the world’s leading research and treatment facilities for patients with monogenic diabetes, can help with testing, appropriate treatment and education. Our team encompasses leading experts in monogenic diabetes diagnosis, research and treatment.
In addition, Kovler houses the Monogenic Diabetes Registry, the first nationwide database of individuals affected by these uncommon forms of diabetes. The registry is designed to track and study monogenic forms of diabetes in individuals on a long-term basis, noting symptoms, genetic patterns in families, and optimal therapies for each patient.
To learn more about monogenic diabetes and the Monogenic Diabetes Registry, visit our monogenic diabetes website.
Clinical research to advance the understanding, treatment, diagnosis and prevention of diabetes is a significant part of our work at Kovler. You can help advance the scientific understanding of diabetes in order to find a cure for the disease by participating in a Kovler clinical trial.