Louis Philipson, MD, PhD

Director, Kovler Diabetes Center
Professor of Medicine

Dr. Philipson is an endocrinologist and a leading world authority on diabetes mellitus. In 2011, he was named as one of America’s Top Doctors by U.S. News & World Report magazine, and in 2016 Chicago Magazine named him a Top Doctor in Endocrinology, Diabetes and Metabolism. His research focuses on the biophysical, molecular and genetic aspects of insulin secretion, and the genetics of diabetes.

Dr. Philipson was a co-discoverer of insulin gene mutations causing neonatal diabetes, a novel class of mutations causing diabetes through beta-cell ER stress. These mutations are now known to be the second most common cause of permanent neonatal diabetes, as well as rare causes of later-onset diabetes. Dr. Philipson, together with his colleagues (Drs. Graeme Bell, Siri Atma Greeley and Rochelle Naylor) established the first United States registry for monogenic diabetes including neonatal diabetes and Mature Onset Diabetes of the Young (MODY).

Dr. Philipson is co-director of the Human Islet Transplantation project at the University of Chicago. He has served as principal investigator on numerous research projects and has been widely published in biomedical journals.

The Kovler diabetes team includes adult and pediatric endocrinologists, educators, nutritionists, nurses, psychologists and podiatrist. Other medical specialists are readily available.  Insulin pumps, glucometers and glucose sensors of all types are part of the program. The team is particularly geared toward referrals and consultations for difficult management problems.

As president of the Chicago/Northern Illinois board of the American Diabetes Association and also a member of its national board, Dr. Philipson has been an invited speaker and presenter at scientific research conferences and symposia worldwide.

Clinical interests:

  • Diabetes
  • Hypoglycemia

Selected publications:

  • Proceedings of the National Academy of Sciences
  • Science
  • Nature
  • Diabetes
  • American Journal of Physiology
  • Journal of Biological Chemistry


  • MD, University of Chicago
  • Internship and Residency, University of Chicago Medical Center

Selected honors and awards:

  • ADA Research Awards
  • National Disease Research Interchange (NDRI) Outstanding Scientist Award
  • 2011 Samuel Eichold II Memorial Award for Contributions in Diabetes, American College of Physicians

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