Here are some clinical trials that are active
 right now!


A Research Study To Examine the Safety of Study Drug, PF06342674

Investigators are conducting a research study to examine the safety of study drug, PF06342674, in the Clinical Resource Center. This drug does not have FDA approval. You may qualify for the study if:

  • You have been diagnosed with type 1 diabetes in the last 2 years.
  • You are age 18 years or older.

You will be asked to:

  • Come to up to 20 study visits
  • Have multiple blood draws, urine samples and ECGs
  • Keep a diary of your blood glucose and insulin levels

Subjects will be reimbursed up to $2500 and receive parking voucher. If you are interested, please contact Tiffany Grant at 773 702 3853 or

A Research Study of Islet Transplantation in People with Unstable or “Brittle” Type 1 Diabetes

Islet transplants are intended to help control blood glucose without insulin injections in advanced type I diabetes by replacing destroyed islets with new ones. No surgery is needed. The islet cells from a deceased donor’s pancreas are taken and injected into a major blood vessel in the subject’s body. The islet cells then begin making insulin. Islet transplant is experimental and Dr. Witkowski, the Principal Investigator at The University of Chicago Medicine is conducting clinical trials to evaluate the long-term benefits and risks of the procedure. Participants must meet the following requirements:

  • Must be between the ages of 18 and 65
  • Must have type 1 diabetes for at least last 5 years
  • Must be on insulin injections or on pump
  • Must be available for clinic visits for the duration of the study
  • Must meet study criteria as evaluated by the Principal Investigator: Dr. Witkowski

For more information on this research study please contact Islet Cell Coordinator: Lindsay Schenck, RN, BSN at 773-702-2504 or visit our website at:

RISE Study: Restoring Insulin Secretion

This research study is being done to examine whether it would be beneficial to give medicines to persons who are at risk for developing Type 2 diabetes or persons who have been recently (within the past year) diagnosed with mild Type 2 diabetes and have not taken medicine to treat it. Usually medications are not prescribed for persons with pre-diabetes or very mild diabetes. We think that giving medicine to people with pre-diabetes or mild diabetes might prevent progression or worsening of these conditions. Participants will be assigned to one of 4 different drugs. This study lasts about 2 years and you will be asked to come to the University for a check-up every 3 months.
You may be eligible to participate if the following are true:

  • Age 20-65
  • Have been diagnosed with Type 2 diabetes in the past year and have never taken medication for diabetes OR if you think you might have pre-diabetes
  • Overweight
  • Do not have a serious medical condition

If you are interested in learning more about the study please leave a message which includes your contact information at 773-702-0011. Please say that you are interested in the RISE study. Someone will contact you within a few days.

Compensation given for participating in the study will be up to $425. You will also receive CTA passes or parking garage stickers. This research is taking place at 8 different Medical Centers. At The University of Chicago Dr. David Ehrmann and Dr. Babak Mokhlesi are conducting the study.

Research Study on Closed-loop Insulin Delivery Systems

You may qualify for the study if:
You are between the age of 18-25, have a diagnosis of type 1 diabetes, are being treated with continuous subcutaneous insulin pump therapy, and participate in moderate–high levels of physical activity as assessed by the Seven Day Physical Activity Recall.

Subjects will be re-imbursed for time and travel.

For more information about this study, please call Elizabeth Littlejohn, MD (773-702-4616) or email

Research Study about Type 2 Diabetes and Sleep Disturbances

We think a diabetes medication may improve sleep disturbances, which are very common in patients with Type 2 diabetes. To better understand this relationship, we are conducting research studies that involve screenings and sleep recording.

If you have type 2 diabetes and are 18 years of age or older, and are interested in learning more about this study, LEARN MORE or call the University of Chicago at 773-795-0141.


Closed-loop Insulin Delivery Systems

Investigators are conducting a research study on closed-loop insulin delivery systems in the Clinical Resource Center.

You May Be Eligible to Participate if You:

  • Are 18-25 years of age
  • You have a diagnosis of type 1 diabetes
  • You are being treated with continuous subcutaneous insulin pump therapy
  • Participate in moderate–high levels of physical activity as assessed by the Seven Day Physical Activity Recall

Subjects will be reimbursed for time and travel.  For more information, please contact Elizabeth Littlejohn, MD, at 773-702-4616 or ELITTLEJ@PEDS.BSD.UCHICAGO.EDU.

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