Here are some clinical trials that are active right now!
FOR ADULTS
Research Study on Closed-loop Insulin Delivery Systems
You may qualify for the study if:
You are between the age of 18-25, have a diagnosis of type 1 diabetes, are being treated with continuous subcutaneous insulin pump therapy, and participate in moderate–high levels of physical activity as assessed by the Seven Day Physical Activity Recall.
Subjects will be re-imbursed for time and travel.
For more information about this study, please call Elizabeth Littlejohn, MD (773-702-4616) or email elittlej@peds.bsd.uchicago.edu.
Research Study about Type 2 Diabetes and Sleep Disturbances
We think a diabetes medication may improve sleep disturbances, which are very common in patients with Type 2 diabetes. To better understand this relationship, we are conducting research studies that involve screenings and sleep recording.
If you have type 2 diabetes and are 18 years of age or older, and are interested in learning more about this study, LEARN MORE or call the University of Chicago at 773-795-0141.
PCOS, Sleep Apnea and Metabolic Risk in Women (DEP Study)
This study involves both outpatient and inpatient testing in the University of Chicago Hospital Clinical Research Center and Sleep Research Laboratory for no more than 3 ½ months
Eligibility:
- Women age 18 to 40
- Diagnosed with PCOS
- Not using birth control pills, patches, or injections
For further information please call the study recruitment line at 773-702-4295 or e-mail PCOS@medicine.bsd.uchicago.edu and ask about DEP Study.
SIROCO Clinical Trial
It is common for patients to suffer from more than one condition that makes them more likely to have heart (cardiovascular) disease. Some of these conditions include high blood pressure, diabetes, obesity, or dyslipidemia (an unhealthy level of fats, or lipids, in the bloodstream). Because patients often suffer from more than one of these conditions at the same time, doctors think that these conditions may have similar root causes.
You may be eligible to participate if you:
• Are 21-75 years old.
• Have an LDL levels >130 mg/dL or >100 in patients with CHD.
• Have metabolic syndrome (3 of the following 5 components):
- Elevated waist circumference (≥102 cm (≥40 inches) in men, ≥88 cm (≥35 inches) in women)
- Elevated triglycerides (≥150 mg/dL (1.7 mmol/L) or on drug treatment for elevated triglycerides)
- Reduced HDL-C (<40 mg/dL (1.03 mmol/L) in men, <50 mg/dL (1.3 mmol/L) in women, or on drug treatment for reduced HDL-C)
- Elevated blood pressure (≥130 mm Hg systolic blood pressure or ≥85 mm Hg diastolic blood pressure or on antihypertensive drug treatment in a patient with a history of hypertension
- Elevated fasting glucose (≥100 mg/dL)
Make an appointment for a fasting blood glucose test, at no cost to you, by contacting Linda Fondren from the Hypertension Disease Unit department at 773-702-7941 or Rolanda J. Flynn at 773-834-4059, Beeper (2400).
EFFORT Clinical Trial
The study is being done to see if a drug shown to lower the risk of heart failure is also effective in reducing the stiffness of your arteries. This will be compared to another drug that also lowers blood pressure. It is thought that reducing stiffness of arteries may provide an additional benefit in reducing risk of death.
Your blood pressure will be checked by a machine (Sphygmocor) that measures how fast your blood moves through the artery. This machine uses a microphone type device that is placed on your skin just above an artery. In addition to this a microphone type device will be placed just above your heart so the pressure in your aorta (the main artery that comes out of your heart to provide blood to the entire body will also be assessed.
Inclusion Criteria:
- Age >50, Established Type 2 diabetics not treated with insulin
- Stage I hypertensives (BP >130/80 mm Hg and <160/100 mm Hg)
- Normally active and judged to be in good health on the basis of medical history and routine laboratory tests
- Must be on an optimal dose of a renin-angiotensin-system (RAS) blocker before randomization unless the patient is intolerant
- BMI ≤ 35
- Hemoglobin A1C ≤ 8.5,
If you complete all study visits, you will receive $250.
Contact Linda Fondren from the Hypertension Disease Unit department at 773-702-7941 or Rolanda J. Flynn at 773-834-4059, Beeper (2400).
FOR YOUNG ADULTS
Closed-loop Insulin Delivery Systems
Investigators are conducting a research study on closed-loop insulin delivery systems in the Clinical Resource Center.
You May Be Eligible to Participate if You:
- Are 18-25 years of age
- You have a diagnosis of type 1 diabetes
- You are being treated with continuous subcutaneous insulin pump therapy
- Participate in moderate–high levels of physical activity as assessed by the Seven Day Physical Activity Recall
Subjects will be reimbursed for time and travel. For more information, please contact Elizabeth Littlejohn, MD, at 773-702-4616 or ELITTLEJ@PEDS.BSD.UCHICAGO.EDU.
