Here are some clinical trials that are active
 right now!


RISE Study: Restoring Insulin Secretion

Are you overweight and worried about developing diabetes?
Do you have a family history of diabetes?
Has a health care provider ever spoken to you about high blood sugar?  Or said you have “borderline diabetes”?

If you answered YES to any of these questions,then you may
be at high risk for developing diabetes.

The RISE Study ( is looking for people like you.  RISE is an NIH-sponsored national research study for people who are at high risk of developing diabetes.  The study will be investigating how to prevent or delay the development of diabetes in people who are at high risk.

Why should you participate in the RISE Study?

Diabetes is a growing problem in adults.  RISE is a chance to learn the best ways to treat prediabetes at its earliest stages and thereby prevent or delay the development of diabetes.  During the study you will receive:
·     The opportunity to improve your health
·     A screening to determine if you have prediabetes
·     Drugs approved to treat diabetes, or placebo (inactive substance)
·     Drugs, lab tests, and medical visits provided at no cost
·     Compensation for study participation

To schedule an appointment and see if you are at risk for developing diabetes, call 773-702-4295 or email

Click here to learn more

A Research Study To Examine the Safety of Study Drug, PF06342674

Investigators are conducting a research study to examine the safety of study drug, PF06342674, in the Clinical Resource Center. This drug does not have FDA approval. You may qualify for the study if:

  • You have been diagnosed with type 1 diabetes in the last 2 years.
  • You are age 18 years or older.

You will be asked to:

  • Come to up to 20 study visits
  • Have multiple blood draws, urine samples and ECGs
  • Keep a diary of your blood glucose and insulin levels

Subjects will be reimbursed up to $2500 and receive parking voucher. If you are interested, please contact Tiffany Grant at 773 702 3853 or

A Research Study of Islet Transplantation in People with Unstable or “Brittle” Type 1 Diabetes

Islet transplants are intended to help control blood glucose without insulin injections in advanced type I diabetes by replacing destroyed islets with new ones. No surgery is needed. The islet cells from a deceased donor’s pancreas are taken and injected into a major blood vessel in the subject’s body. The islet cells then begin making insulin. Islet transplant is experimental and Dr. Witkowski, the Principal Investigator at The University of Chicago Medicine is conducting clinical trials to evaluate the long-term benefits and risks of the procedure. Participants must meet the following requirements:

  • Must be between the ages of 18 and 65
  • Must have type 1 diabetes for at least last 5 years
  • Must be on insulin injections or on pump
  • Must be available for clinic visits for the duration of the study
  • Must meet study criteria as evaluated by the Principal Investigator: Dr. Witkowski

For more information on this research study please contact Islet Cell Coordinator: Lindsay Schenck, RN, BSN at 773-702-2504 or visit our website at:

Research Study on Closed-loop Insulin Delivery Systems

You may qualify for the study if:
You are between the age of 18-25, have a diagnosis of type 1 diabetes, are being treated with continuous subcutaneous insulin pump therapy, and participate in moderate–high levels of physical activity as assessed by the Seven Day Physical Activity Recall.

Subjects will be re-imbursed for time and travel.

For more information about this study, please call Elizabeth Littlejohn, MD (773-702-4616) or email

Research Study about Type 2 Diabetes and Sleep Disturbances

We think a diabetes medication may improve sleep disturbances, which are very common in patients with Type 2 diabetes. To better understand this relationship, we are conducting research studies that involve screenings and sleep recording.

If you have type 2 diabetes and are 18 years of age or older, and are interested in learning more about this study, LEARN MORE or call the University of Chicago at 773-795-0141.


Closed-loop Insulin Delivery Systems

Investigators are conducting a research study on closed-loop insulin delivery systems in the Clinical Resource Center.

You May Be Eligible to Participate if You:

  • Are 18-25 years of age
  • You have a diagnosis of type 1 diabetes
  • You are being treated with continuous subcutaneous insulin pump therapy
  • Participate in moderate–high levels of physical activity as assessed by the Seven Day Physical Activity Recall

Subjects will be reimbursed for time and travel.  For more information, please contact Elizabeth Littlejohn, MD, at 773-702-4616 or ELITTLEJ@PEDS.BSD.UCHICAGO.EDU.

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