Silvana Pannain, MD

Assistant Professor of Medicine

Dr. Pannain is an endocrinologist and bariatric physician providing advanced endocrinology care for patients with weight problems or endocrine disorders including obesity, diabetes, thyroid disease, pituitary disease, lipid disorders, adrenal disease and metabolic syndrome. She applies highly specialized biochemical testing methods and the newest drug treatments available.

Dr. Pannain also serves as director of Chicago Weight, a multidisciplinary weight management program at the University of Chicago. She works closely with teams of specialists – including behavior therapists, dietitians, exercise therapists, bariatric surgeons, cardiologists, lipidologists, hypertension specialists and sleep specialists – to develop comprehensive weight management plans for adult patients. Chicago Weight offers customized weight management in an interdisciplinary, comprehensive care model.

Dr. Pannain investigates the metabolic and endocrine aspects of chronic partial sleep loss, which is generally considered a risk factor for obesity and insulin resistance. Additionally, she is studying the effects of gastric bypass surgery on metabolism, sleep and hunger.

Research interests:

Obesity, metabolic syndrome and related health conditions, such as obstructive sleep apnea and diabetes

Clinical interests:

  • General endocrinology
  • Obesity
  • Metabolic syndrome
  • Heart disease
  • Sleep disorders


  • Medical School, Internship and Residency: University of Naples, Italy
  • Internship and Residency: Montefiore Medical Center, Bronx, New York
  • Fellowship: University of Chicago Medical Center