Louis H. Philipson, MD, PhD, FACP

Louis Philipson, MD, PhD, is Director of Kovler Diabetes Center and Professor of Medicine at the University of Chicago. He is an endocrinologist and a leading world authority on diabetes mellitus. In 2011, he was chosen one of America’s Top Doctors by U.S. News & World Report magazine. His research focuses on the biophysical, molecular and genetic aspects of insulin secretion, and the genetics of diabetes.

Dr. Philipson was a co-discoverer of insulin gene mutations causing neonatal diabetes, a novel class of mutations causing diabetes through beta cell ER stress. These mutations are now known to be the second most common cause of permanent neonatal diabetes as well as rare causes of later onset diabetes. Dr. Philipson, together with his colleagues Drs Bell, Greeley and Naylor, is a resource for monogenic diabetes in the United States, following more than 100 patients diagnosed with neonatal diabetes and many others with MODY type diabetes. The team has also recently established the first United States registry for neonatal and monogenic diabetes.

Dr. Philipson is co-director of the Human Islet Transplantation project at the University of Chicago. He has served as principal investigator on numerous research projects and has been widely published in biomedical journals including the Proceedings of the National Academy of Sciences, Science, Nature, Diabetes, American Journal of Physiology and the Journal of Biological Chemistry.

Clinically he focuses on type 1 diabetes and complicated type 2 diabetes, monogenic diabetes and hypoglycemia. The Kovler diabetes team includes adult and pediatric endocrinologists, educators, nutritionists, nurses, psychologists and podiatrist. Other medical specialists are readily available.  Insulin pumps, glucometers and glucose sensors of all types are part of the program. The team is particularly geared towards referrals and consultations for difficult management problems.

Currently President of the Chicago/Northern Illinois board of the American Diabetes Association and also a member of its National Board, he has been an invited speaker and presenter at scientific research conferences and symposia worldwide. Dr. Philipson also is the recipient of numerous awards including ADA Research Awards and the National Disease Research Interchange (NDRI) Outstanding Scientist Award. Most recently he was named the 2011 recipient of the Samuel Eichold II Memorial Award for Contributions in Diabetes by the American College of Physicians.

Clinical Interests

  • Diabetes
  • Hypoglycemia

Medical School

University of Chicago

Internship & Residency

University of Chicago Medical Center


American College of Physicians

American Diabetes Association

Juvenile Diabetes Research Foundation International

Midwest Society for Clinical Research

European Society for Study of Diabetes


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